Cantargia tar in kapital – CAN04 ska utvecklas - Omni Ekonomi

Cantargia får patentgodkännande i Kina för CAN04 - Finwire

About CAN04 The antibody CAN04 binds strongly to the target IL1RAP and functions both though ADCC as well as blocking IL-1α and Cantargia AB gav idag en uppdatering om framstegen i dess utvecklingsprojekt kring antikropparna CAN04 och CAN10 till följd av den pågående COVID-19-pandemin. Den initiala doseskaleringsfasen för CAN04 har avslutats för både icke-småcellig lungcancer (NSCLC) och bukspottkörtelcancer (PDAC). Cantargia utvecklar antikroppsbaserade läkemedel mot interleukin-1 receptor accessory protein (IL1RAP). Huvudprojektet CAN04 befinner sig i fas IIa klinisk utveckling för cancerbehandling och CAN10 är i preklinisk utveckling mot autoimmunitet och inflammationssjukdomar. Cantargia utvecklar antikroppsbaserade läkemedel mot interleukin-1 receptor accessory protein (IL1RAP). Antikroppen CAN04 binder IL1RAP med hög affinitet och fungerar både genom s.k.

Överföringen av GMP-produktionen till Patheon Biologics B.V ingår i bolagets långsiktiga strategi. Cantargia AB ("Cantargia") meddelade idag att nya prekliniska resultat, som stödjer kombination av den kliniskt studerade antikroppen CAN04 med platinabaserade cellgifter, kommer presenteras vid två posterpresentationer på 2020 Annual Meeting of the American Association for Cancer Research (AACR), den 22-24 juni. Cantargia utvecklar antikroppsbaserade läkemedel mot interleukin-1 receptor accessory protein (IL1RAP). Antikroppen CAN04 binder IL1RAP med hög affinitet och verkar både genom blockad av IL-1-signalering och s.k. Antibody-Dependent Cellular Cytotoxicity (ADCC). Prekliniska data visar att CAN04 kan öka effekten av cellgifter. CAN04 i nivå med de resultat som den nya immunomodulerande antikroppen Keytruda (pembrolizumab, Merck) nyligen visat i en fas 2-studie (KEYNOTE-799) på 216 svårt sjuka NSCLC-patienter (icke operabelt stadium III).

Cantargias produktkandidat CAN04 visar mycket god säkerhet

Preclinical data show that CAN04 increases the efficacy of chemotherapy. Cantargia AB today announced that the IND application regarding the antibody CAN04 has been approved by the US FDA. CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), Cantargia develops antibody-based pharmaceuticals against IL1RAP. The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP).

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CANTA. NASDAQ Stockholm. Click to login. 15.94. +0.06. +0.38%. MARKET CAP. 1.2B Cantargia: CAN04 ASCO 2019 presentation.

Antibody-Dependent Cellular Cytotoxicity (ADCC) och blockering av IL-1-signalering. Cantargia utvecklar antikroppsbaserade läkemedel mot IL1RAP. Antikroppen CAN04 binder IL1RAP med hög affinitet och fungerar både genom s.k. Antibody-Dependent Cellular Cytotoxicity (ADCC) och blockad av signaler från IL-1-systemet. Prekliniska data visar att CAN04 ökar effekten av cellgifter. Cantargia är nu på väg att bredda utvecklingsaktiviteterna och nästa steg är en fas Ib studie där CAN04 studeras i kombination med den PD1-bindande antikroppen pembrolizumab (Keytruda[®]). FDA har nu godkänt studien och kommande steg innan patienter kan starta behandling inkluderar godkännande från etikkommittéer samt andra administrativa åtgärder.
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The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and Cantargia´s antibody CAN04 (nidanilimab) is investigated in an open label three-armed phase IIa clinical trial, CANFOUR. Here, CAN04 is examined as monotherapy or in chemotherapy combinations in patients with non-small cell lung cancer (NSCLC) or pancreatic cancer (PDAC). Cantargia submits IND application for CAN04 Cantargia AB today announced that the application for a US IND regarding the antibody CAN04 has been submitted to the US FDA. 2021-03-10 (R) Cantargia submits application to start new clinical trial investigating antibody CAN04 and FOLFIRINOX in pancreatic can 2021-03-01 Cantargia provides business updates at investor conferences during March 2021 (R) = Regulatory press releases Cantargia develops antibody-based pharmaceuticals against IL1RAP. The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and blockade of IL-1 signaling. Preclinical data show that CAN04 increases the efficacy of chemotherapy. Cantargia AB today announce new positive preclinical data which defines a novel additional development opportunity for Cantargias antibody CAN04.

no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases. The basis for this is the protein IL1RAP that is The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. The main project, the antibody CAN04, is being studied clinically as combination therapy with chemotherapy or immune therapy with a primary focus on non-small cell lung cancer and pancreatic cancer. 2019-8-23 · 2015, Cantargia has advanced CAN04 to phase IIa clinical development for potential use in the treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer (PDAC). Cantargia develops antibody-based pharmaceuticals against the interleukin 1 receptor accessory protein (IL1RAP).
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The study is designed for 20 patients in monotherapy and approximately 30 patients in each combination arm. 2021-3-1 · The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. The main project, the antibody CAN04, is being studied clinically 2021-4-8 · STOCKHOLM, March 10, 2021 /PRNewswire/ -- Cantargia AB today announced the submission of a clinical trial application investigating antibody CAN04 in … 2021-3-15 · Cantargia is a clinical-stage biotechnology company based in Sweden, established in 2009 and listed on the Nasdaq Stockholm main market. It is developing two assets against IL1RAP, CAN04 and CAN10. The lead clinical trial is a Phase IIa CANFOUR study with CAN04 in non-small cell lung cancer and pancreatic cancer. "Cantargia’s decision to increase the level of ambition in the CAN04 project is among the most important and the most intensified in the company's history.

It is developing two assets against IL1RAP, CAN04 and CAN10. The lead clinical trial is a Phase IIa CANFOUR study with CAN04 in non-small cell lung cancer and pancreatic cancer. "Cantargia’s decision to increase the level of ambition in the CAN04 project is among the most important and the most intensified in the company's history. This marks a major step to enhance the value of the CAN04 project and take greater advantage of the potential around the target IL1RAP (Interleukin 1 Receptor Associated Protein).
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Investeringstipset Lundabolaget Cantargias målsökande

(Direkt) Bioteknikbolaget Cantargia avser göra en riktad nyemission av aktier motsvarande En muntlig presentation med titeln “Results from a First-in-man, Open label, Safety and tolerability Trial of CAN04 (Nidanilimab), a Fully Forskningsbolaget Cantargia har gjort viktiga framsteg under hösten och är nu igång med en klinisk studie på sin läkemedelskandidat CAN04. Bioteknikbolaget meddelar positiva preklindata för kandidaten CAN04 i urinblåsecancer. Nästa år inleder Lundabolaget Cantargia patientstudier för sin antikropp, CAN04, som man hoppas kan bli ett helt nytt behandlingsalternativ för flera Cantargia har anlitat Carnegie Investment Bank AB (publ), Kempen & Co ”Under 2020 har arbetet med CAN04 signifikant framskridit och de Genom den Riktade Emissionen tillförs Cantargia cirka 564 miljoner kronor Publicerad den 13 Cantargia: CAN04 ASCO 2019 presentation. Studien kommer undersöka Can04 i kombination med Mercks Cantargia håller för närvarande på med en fas 2a-studie med Can04 vid CAN04 binder interleukin 1 receptor accessory protein (IL1RAP), blockerar Cantargia erhåller patentgodkännande för antikroppen CAN04 STOCKHOLM (Nyhetsbyrån Direkt) Forskningsbolaget Cantargias läkemedelskandidat Can04 har ett bredare angreppssätt än Novartis canakinumab (ACZ885) Cantargia AB:s (”Cantargia”) produktkandidat CAN04 genomgår de sista testerna innan ansökan om kliniska prövningar. Den nyligen aktien Cantargia (CANTA). Analyser, rekommendationer & riktkurser för Cantargia aktien. Cantargia: Stärkta i vår uppfattning om CAN04.

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Cantargia: muntlig presentation av fas I data för antikroppen

The lead project CAN04 is in phase IIa clinical development for treatment of cancer Detailed Description: CAN04 is a first-in-class fully humanized and ADCC enhanced monoclonal antibody, targeting the Interleukin 1 Receptor Accessory Protein (IL1RAP). The CAN04 strategy is to attack the IL1RAP target molecule using an effective antibody-based cancer treatment. 2021-2-5 · Cantargia reports positive interim data from ongoing phase IIa combination study with antibody CAN04 Mon, Dec 02, 2019 10:30 CET. Cantargia AB today announced the first interim data with antibody CAN04 in combination with chemotherapy in the ongoing phase IIa CANFOUR study.

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Utifrån resultaten av fas 1-delen i studien kommer Cantargia att kunna specificera hur den fortsatta studien ska utformas och vilka substanser den då ska kombineras med.

2021-3-1 · Cantargia AB (publ), reg. no. 556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases. The basis for this is the protein IL1RAP that is The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform.